Excellence Cluster · Karolinska Institutet

Cancer Compass

Navigating the future of cancer care through multimodal AI — guiding patients, clinicians, and researchers toward better outcomes.

VR & Vinnova Excellence Cluster · Sweden · 2027–2031

AI that thinks with clinicians,
not instead of them

Cancer Compass is a national excellence cluster led by Karolinska Institutet, bringing together leading researchers in oncology, artificial intelligence, and data science to fundamentally transform how cancer is diagnosed and treated.

The cluster develops multimodal agentic AI that integrates imaging, genomics, pathology, and clinical data to map each patient's unique disease trajectory. By combining cutting-edge deep learning with causal reasoning and explainability, Cancer Compass builds AI that clinicians can understand, trust, and act on.

Funded by the Swedish Research Council (VR) and Vinnova as part of the Excellence Clusters for Groundbreaking Technologies initiative, the cluster spans academia, healthcare, and industry — connecting Sweden's most comprehensive cancer cohorts with world-class AI research.

Three cancer pillars, one AI platform

Prostate Cancer

Anchored in Sweden's world-leading STHLM0/3-MRI and ProBio cohorts, spanning 37 hospitals across four countries, with over 15 years of longitudinal data.

Breast Cancer

Integrating mammography, MRI, and genomic biomarkers across the ScreenTrust cohorts, led by world-class breast radiology expertise at KI.

Colorectal Cancer

Leveraging the ALSCCA cohort with colonoscopy AI, CT/MRI imaging, and molecular markers including MSI, KRAS, and BRAF profiling.

Built on Sweden's strongest cancer data

Cancer Compass connects some of the most comprehensive cancer cohorts in the world, combining clinical records, multi-omics data, imaging, and pathology at a scale that makes genuine AI breakthroughs possible.

The cluster also encompasses ethics, law, and patient equity — ensuring that AI innovation in oncology is trustworthy, transparent, and fair.

37+
Hospitals in prostate cohort
15+
Years of longitudinal data
3
Cancer pillars
4
Countries in collaboration